Kayamkani Abedulla Khan; Ali Mohamed AlKatsha; Mohammed Abdulghani Sarhan; Fawaz Mashaan Abuhamar; Rawaf Abdulrzaq; Aejaz A. Khan; S. M. Shakeel Iqubal; Muazzam Sheriff Maqbul
Abstract
This study is planned to assess the profile of drug-drug interactions in the medications prescribed to metabolic syndrome patients and also to identify the possible predictors for potential drug-drug interactions. Materials and Methods: A cross-sectional study was conducted from 25th Jan to 1st April ...
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This study is planned to assess the profile of drug-drug interactions in the medications prescribed to metabolic syndrome patients and also to identify the possible predictors for potential drug-drug interactions. Materials and Methods: A cross-sectional study was conducted from 25th Jan to 1st April 2019 to check the drug interactions in ambulatory metabolic syndrome patients in Jeddah, Saudi Arabia. A sample size of 142 patients was included in the study. The prescriptions were analyzed for potential drug interactions using Lexi-Interact Online and Medscape online software to check drug-drug interactions. Results: It is observed that as an average 3.85 drug per prescription was prescribed. We observed 55 prescriptions are containing incomplete patient information that is 48.6% of prescriptions. The 62% of patients of this study were more than 60 years. We found a maximum number of prescriptions were found 4-6 drugs per prescription 60.56 % and 78.12 % interactions were moderate interaction and 3.9 % interaction found were major interactions. Conclusion: It was observed that the number of DDIs increased linearly with the number of drugs and age. The majority of interactions was pharmacodynamic in mechanism and showed moderate severity.
Kayamkani Abedulla Khan; Saif Mohammed Al-ghamdi; Nawaf Mohammed Al-ghamdi; Abdullah Radwan Al-saqqa; Hashim Khalid Halawani; Aejaz A. Khan; S. M. Shakeel Iqubal; Muazzam Sheriff Maqbul; Noorulla Khan Mayana
Abstract
Irrational drug prescribing is considered one of the prime challenges for the healthcare sectors worldwide, leading to baneful outcomes in patients. The World Health Organization (WHO) drug use indicators include prescribing indicators, patient care indicators and facility indicators and prescribing ...
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Irrational drug prescribing is considered one of the prime challenges for the healthcare sectors worldwide, leading to baneful outcomes in patients. The World Health Organization (WHO) drug use indicators include prescribing indicators, patient care indicators and facility indicators and prescribing indicators measure the performance of health care providers in several key dimensions related to the appropriate use of drugs. Patient care indicators are used to understand the way drugs are used. To evaluate the trends and issues related to prescription, patient care and facility at outpatient clinics in Jeddah and to contrast that to the WHO drug use indicators. A Cross-sectional study conducted between January to April 2019. A total of 153 prescriptions were collected from outpatient clinics of private and governmental hospitals were analyzed according to WHO guidelines. The statistical calculations were performed using Microsoft excel software. The results illustrate that the average number of drugs per prescription was 4.56 and the percentage of encounter with antibiotics was 8.4. A comparatively encouraging observations were observed during generic prescribing as it was observed to be 54.2%, the percentage of encounters with injection was 7.8 and the percentage of drugs prescribed from essential drug list (EDL) or formulary was 92%. The prescribed drugs average number per encounter was greater than what was considered ideal according to WHO standards; the other issue found was a lower percentage of generic prescribing compared to WHO ideal value, the rest of prescribing indicators including the prescribing from the essential drug list was almost similar to the ideal value recommended by the WHO (100%).
Tasneem Mohammed; Aejaz A. Khan; S. M. Shakeel Iqubal; Touseef Begum
Abstract
Anisoles and Pyridines undergo acetylation and formylation under non-classical Vilsmeier-Haack conditions. The reactants are grinded vigorously in a mortar for about 25 to 30 min at room temperature with a pestle. The introduction of formyl and acetyl groups under solvent free conditions is a unique, ...
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Anisoles and Pyridines undergo acetylation and formylation under non-classical Vilsmeier-Haack conditions. The reactants are grinded vigorously in a mortar for about 25 to 30 min at room temperature with a pestle. The introduction of formyl and acetyl groups under solvent free conditions is a unique, fast and efficient method which has not been reported in literature so far.
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