Document Type : Research Article
Authors
1 Department of General Science, Ibn Sina National College for Medical Studies, Jeddah, Kingdom of Saudi Arabia
2 Department of Pharmaceutical Science, Ibn Sina National College for Medical Studies, Jeddah, Kingdom of Saudi Arabia
Abstract
Anisoles and Pyridines undergo acetylation and formylation under non-classical Vilsmeier-Haack conditions. The reactants are grinded vigorously in a mortar for about 25 to 30 min at room temperature with a pestle. The introduction of formyl and acetyl groups under solvent free conditions is a unique, fast and efficient method which has not been reported in literature so far.
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