Document Type : Research Article

Authors

• Anand Aswar ¹
• Nilesh Govindrao Salunkhe ²
• Chandrashekhar Arun Ladole ²
• Nikita Vinod Thakare ³
• Jagruti Manish Barabde ²

¹ Department of Chemistry, Professor, SGBA University, Amravati, India

² Department of Chemistry, Sant Gadge Baba Amravati University, Amravati, 444602, India

³ Department of Chemistry, Elphinstone College, Mumbai, M.G. Road, Mumbai, 400032, India

Abstract

In the present study, use of MgFe₂O₄@SiO₂-SO₃H as an efficient, green, magnetically recoverable & recyclable catalyst for micro-wave assisted solvent free synthesis of 2,3-dihydroquinazolin-4(1H)-ones reaction pathway is presented. The superiorities of this method are higher conversion rate, shorter reaction time, easy isolation of product and reusability of catalyst without remarkable loss of activity. The synthesized 2,3-dihydroquinazolin-4(1H)-ones derivatives were assessed for their antimicrobial and antifungal activity; where, the most of these compounds exhibit potent antibacterial and antifungal activities against various bacteria and fungi.
 

Keywords

• Magnetically recoverable catalyst
• Microwave assisted
• 2
• 3-dihydroquinazolin-4(1H)-ones
• antibacterial and antifungal activity