A Simple and Convenient Synthesis of 2, 3-dihydroquinazolin-4(1H)-one Derivatives using MgFe2O4@SiO2-SO3H Catalyst

In the present study, use of MgFe₂O₄@SiO₂-SO₃H as an efficient, green, magnetically recoverable & recyclable catalyst for micro-wave assisted solvent free synthesis of 2,3-dihydroquinazolin-4(1H)-ones reaction pathway is presented. The superiorities of this method are higher conversion rate, shorter reaction time, easy isolation of product and reusability of catalyst without remarkable loss of activity. The synthesized 2,3-dihydroquinazolin-4(1H)-ones derivatives were assessed for their antimicrobial and antifungal activity; where, the most of these compounds exhibit potent antibacterial and antifungal activities against various bacteria and fungi.

Keywords:

Magnetically recoverable catalyst

Microwave assisted

3-dihydroquinazolin-4(1H)-ones

antibacterial and antifungal activity

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