Hediyeh Nejati Rad; Aliasghar Behnamghader; Mojgan Bagheri; Masoud Mozafari
Abstract
In this study, mesoporous bioactive glass 77S was synthesized by sol-gel method using two different ionic and nonionic surfactants. Physical-chemical properties of synthesized Bioglass were studied using techniques include X-ray diffraction, scanning electron microscopy, nitrogen adsorption and Fourier ...
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In this study, mesoporous bioactive glass 77S was synthesized by sol-gel method using two different ionic and nonionic surfactants. Physical-chemical properties of synthesized Bioglass were studied using techniques include X-ray diffraction, scanning electron microscopy, nitrogen adsorption and Fourier transform infrared spectroscopy. The results showed that using nonionic and ionic surfactants increased specific surface area by 3 and 5 times, respectively. By determining the silicon release in three different temperatures, the activation energy values of Si-O-Si for sample with surface area of 161 and 94 m 2 /g were calculated 1/10 and 1/5 of control glass with surface area of 34 m 2 /g. The pH of sample was evaluated in solutions buffered with TRIS. pH analysis results suggested a direct relation between surface area and pH changes, the greatest increase in pH was observed in the sample with the highest surface area. Moreover, the in vitro bioactivity test was also conducted in simulated body fluid (SBF) and formation of apatite layer was evaluated by scanning electron microscopy and X-ray diffraction after a day.
Vibha C; Lizymol P P
Abstract
Novel inorganic-organic hybrid resins [IOHRs] containing mixture of alkoxides of calcium/magnesium/zinc with polymerizable dimethacrylate groups were synthesised using a simple single-pot modified sol-gel method. Objective of the present study is to investigate the impact of calcium content over bioactivity, ...
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Novel inorganic-organic hybrid resins [IOHRs] containing mixture of alkoxides of calcium/magnesium/zinc with polymerizable dimethacrylate groups were synthesised using a simple single-pot modified sol-gel method. Objective of the present study is to investigate the impact of calcium content over bioactivity, polymerization shrinkage, and physico mechanical properties of bioactive IOHR containing mixture of alkoxides of calcium/magnesium/zinc having polymerizable methacrylate groups, along with various fillers they can be used as a dental restorative material. Various formulations with varying concentration of inorganic content were used during the synthesis. The concentration of inorganic content was optimised as 0.1% by weight of with respect to the silane. This optimised formulation based photocured composite [CMZ2] showed better DTS (35-40 MPa), FS (65-70 MPa), VHN (140-146 kg/mm 2 ), possess low shrinkage, non-cytotoxic in nature, bioactive with good cell adhesion and cell proliferation properties. CMZ2 was found to be a potential novel dental composite.
V. Sarath Chandra; K. Elayaraja; R. V. Suganthi; M. I. Ahymah Joshy; I. Sulania; P.K. Kulriya; K. Asokan; D. Kanjilal; S. Narayana Kalkura
Abstract
Hydroxyapatite (HAp, Ca10(PO4)6(OH)2) is the main inorganic component of hard tissues like bone and teeth. HAp incorporated with magnetic ions, play an important role in cell separation, magnetic resonance imaging (MRI), targeted drug delivery and in hyperthermia treatment of cancer. In this study, the ...
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Hydroxyapatite (HAp, Ca10(PO4)6(OH)2) is the main inorganic component of hard tissues like bone and teeth. HAp incorporated with magnetic ions, play an important role in cell separation, magnetic resonance imaging (MRI), targeted drug delivery and in hyperthermia treatment of cancer. In this study, the effect of 60 MeV Si 5+ ion on the hydrothermally synthesized Fe 3+ doped hydroxyapatite (Fe-HAp, 33 nm) was investigated. At higher fluences, partial amorphization with an increase in the cluster size and surface roughness was observed. Depending on the ion fluence, pores ranging from 300 to 360 nm in size were produced. Irradiated Fe-HAp samples showed enhanced haemocompatibility and bioactivity. The drug (amoxycillin, AMX) loaded irradiated samples exhibited high antimicrobial activity.
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