Anshuman Mishra; Yogesh Shukla; Ashutosh Tiwari
Abstract
COVID-19 risk spread rapidly with several clinical manifestations and public health challenges. Research and innovation in advanced materials should be focused on solving critical problems associated with diagnosis, treatment and control models. Important challenges of COVID-19 public health system indicated ...
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COVID-19 risk spread rapidly with several clinical manifestations and public health challenges. Research and innovation in advanced materials should be focused on solving critical problems associated with diagnosis, treatment and control models. Important challenges of COVID-19 public health system indicated to need of solutions based on cost, quality and universal availability in sustainable model. Standard healthcare models can be achieved by advanced technology of Artificial intelligence, IoT, Database analytics and advanced materials more effectively for mass community. Next-generation (“smart”) materials have capacity to contribute to theranostics models in better way with high accuracy in terms of performance and reliability. In summary, engineered nanoparticles and advanced technologies have translational potential. Being public health professionals, technologist and materials researchers involved in the prognosis research should develop certain priorities for the society.
Anshuman Mishra; Santanu Patra; Sudheesh K. Shukla; Pavan Pandey; Yogesh Shukla; Pavel Osmera; Pankaj Yadav; Manoj Pandey; Rajiv Gupta; Franck Molina; Carlos E. Semino; Ashutosh Tiwari
Abstract
World Health Organization (WHO) has expressed great concern about the pandemic of Coronavirus (COVID-19) and said that there is a need to control it at the high end. To strengthen this fight against COVID-19, International Association of Advanced Materials (IAAM) intends to provide a forum for high-tech ...
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World Health Organization (WHO) has expressed great concern about the pandemic of Coronavirus (COVID-19) and said that there is a need to control it at the high end. To strengthen this fight against COVID-19, International Association of Advanced Materials (IAAM) intends to provide a forum for high-tech healthcare. Foreseeing the current crisis, IAAM called a multi-lateral consortium to discuss the possibilities of developing a medical technology to control the spreading of coronavirus with the help of interdisciplinary experts from multiple countries. This innovation is perpetuated to create multi-lateral cooperation in the area of ‘healthcare innovation and technology’. Adaptation of advanced technologies and their logical integration according to contemporary healthcare measures could be a smart strategy for epidemic management activities. Establishing an advanced phenotype model for prognosis is an important step in the prevention of infectious disease management such as COVID-19. This article has overviewed the global situation, efforts, and prospective of coronavirus pandemic.
Ayushi Tiwari; Anshuman Mishra
Abstract
Diabetes mellitus is a serious life-time health issue which has been increasing among the greater population, approximately 285 million people carrying this disease worldwide. In this study, we have functionalised the gold nanoparticles (AuNPs) with biocatalytic enabled optical property, it is the subject ...
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Diabetes mellitus is a serious life-time health issue which has been increasing among the greater population, approximately 285 million people carrying this disease worldwide. In this study, we have functionalised the gold nanoparticles (AuNPs) with biocatalytic enabled optical property, it is the subject of the study for detecting glucose towards the development of photometric nano-transducer. The citrate capped AuNPs were used to warrant the electrostatic self-assembly of glucose oxidase (GOx) in the colloidal state. Glucose biocatalysis was studied through the nano-optical function of glucose on the surface of AuNPs. Using surface plasmonic resonance as analytical technique, we have determined the molecular binding interaction between glucose molecule and AuNPs surface. Based on the visible spectrum, successful immobilization of GOx onto AuNPs was demonstrated. The GOx functionalized AuNP exhibits catalytic activities for the oxidation of glucose and resulting change in the absorption peak of colloidal bio-assembly. It was observed that the absorbance at 520 nm was proportional to the concentration of glucose in the test samples. The Lambert-Beer law expresses the linear relationship between the absorbance and glucose concentration at a fixed wavelength, i.e., λmax at 520 nm. The precise detection of glucose is essential to monitor the biological level of glucose in the body. It can be concluded that the nano-(bio) gold surface exhibits a rapid photometric response with changes of glucose concentration in the test samples.
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