COVID-19 risk spread rapidly with several clinical manifestations and public health challenges. Research and innovation in advanced materials should be focused on solving critical problems associated with diagnosis, treatment and control models. Important challenges of COVID-19 public health system indicated to need of solutions based on cost, quality and universal availability in sustainable model. Standard healthcare models can be achieved by advanced technology of Artificial intelligence, IoT, Database analytics and advanced materials more effectively for mass community. Next-generation (“smart”) materials have capacity to contribute to theranostics models in better way with high accuracy in terms of performance and reliability. In summary, engineered nanoparticles and advanced technologies have translational potential. Being public health professionals, technologist and materials researchers involved in the prognosis research should develop certain priorities for the society.