Copper hydroxide nanowires were synthesized from copper chloride dihydrate and sodium hydroxide in the presence of Pistachio leaf extract at room temperature. The results of scanning electron microscopy (SEM) exhibited that the copper hydroxide Cu(OH)2 are nanowires in shape and having an average diameter of ca. 10 nm and lengths of up to 500 nm . The Fourier transfor infrared spectroscopy (FT-IR) results examined the bioactive functional groups , which acts as dispersing, binding and capping agent for the copper hydroxide nanowires. X-ray diffraction (XRD) spectra confirmed the copper hydroxide nanoparticles crystalline in nature. The current research introduces a new, simple, and rapid route for the in –laboratory synthesis of copper hydroxide nanowires. This facile and green approach may provide a useful tool to large scale synthesis other copper nanoparticles that have potential biotechnology.