The current research is aimed at design and 3D development of a degradable cylindrical mesh cage porous bioimplant for fixation to a segmental femur bone defect. The finite element analysis (FEA) was carried out to obtain the bone-bioimplant interface deformation and stress generated. The cylindrical mesh cage bioimplant was designed using a range of metallic biomaterials such as Magnesium (Mg) alloy (AZ31), Ti alloy (Ti-6Al-4V) and Stainless Steel (SS316L). The FEA was carried out for bone-bioimplant assembly in static and dynamic conditions. FEA results demonstrated that the values of the interface von-mises stress for the AZ31 Mg-alloy based bioimplant could fall with in the clinical acceptable domain at which the stress sheilding issues could be avoided. The results further suggested that Mg-based bioimplants could be promising and better alternative for use as a porous scaffold for repair and regeneration of a segmental femur bone defect.