Mangroves are salt-tolerant plants of tropical and subtropical intertidal regions of the world. The specific regions where these plants occur are termed as 'mangrove ecosystem'. They are having an ecological role as primary producers. In future there is a need to find out natural compounds to come over against chemical compounds. As these compounds reported to have carcinogenic effects. An attempt was made to find out largest sources of plants, the mangroves. They are facing various types of stresses; they are rich in several secondary metabolites. So, some mangrove barks are tested as a new source as a bio ceramic material by using bone marrow mesenchymal stem cells (BMMSCs). From the study it is revealed that among all tested barks, prop root bark of Rhizophora mucronata shows higher biocompatibility for cell adhesion. Thus, this study will enlighten the use of natural products to replaces chemical health hazards for ceramic material as ecofriendly materials.