Ganeshlenin Kandasamy; Atul Sudame; Dipak Maity
Abstract
Herein, we have reported an easy process for the synthesis of superparamagnetic iron oxide nanoparticles (SPIOs, with a size of ~ 10 nm), where these SPIOs are surface-functionalized with novel pi-electron rich surfactants such as 1,4-benzene dicarboxylic acid (BDA) and 2-amino-1,4-benzene dicarboxylic ...
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Herein, we have reported an easy process for the synthesis of superparamagnetic iron oxide nanoparticles (SPIOs, with a size of ~ 10 nm), where these SPIOs are surface-functionalized with novel pi-electron rich surfactants such as 1,4-benzene dicarboxylic acid (BDA) and 2-amino-1,4-benzene dicarboxylic acid (ABDA). The BDA/ABDA capped SPIOs have demonstrated well crystalline character, excellent colloidal stability, and high saturation magnetization. Moreover, these capped SPIOs have shown good heating ability in magnetic-hyperthermia studies under an alternating magnetic field at a medically suitable frequency, as compared to the previously reported SPIOs based heating-agents. Thus, the as-prepared BDA/ABDA-SPIOs can be used as promising heating agents for magnetic-hyperthermia based biomedical applications.
Faruq Mohammad; Hamad A. Al-Lohedan; Hafiz N. Al-Haque
Abstract
Hybrid materials based on metals and natural polymers are a promising class of nanocomposites; there is an increasing interest in metal nanoparticles (NPs) due to some fascinating characteristics associated with their nanosizes such as optical, conducting, catalytic, mechanical, sensing and superparamagnetic ...
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Hybrid materials based on metals and natural polymers are a promising class of nanocomposites; there is an increasing interest in metal nanoparticles (NPs) due to some fascinating characteristics associated with their nanosizes such as optical, conducting, catalytic, mechanical, sensing and superparamagnetic properties. Despite these favorable properties, the natural tendency of NPs for aggregation, high reactivity due to surface charges, and high rate of toxicity are limiting their applicability in biomedical sector. Chitosan, a naturally available amino polysaccharide biopolymer obtained from the exoskeleton of crustaceans (crabs and shrimp) and cell walls of fungi, displays unique polycationic, porous, chelating, bioadhesive and film-forming properties. The in-built characteristics of chitosan biopolymer can be utilized to alter the negative shades of metal NPs, thereby enhancing the applications in many different areas. The incorporation of chitosan significantly affects the steric stabilization of metal colloids, creates extra functional groups for biomolecule conjugation, renders the NPs suitable for bio-markers, protects metal ions from further oxidation/reduction by means of polymer coordination and has a control over toxicity. Thus by taking advantage of the additional features offered by the combination of chitosan and metal NPs, this report is designed to provide an overview about the metal NPs type, synthesis and applications in bioengineering and biomedical sector. Starting with the influencing properties due to their combination, we further reviewed the literature related to chitosan and metal NPs applicable for medicine with a specific focus on cancer diagnosis and treatment, advanced drug delivery, tissue engineering and surgical aids, to mention some.
Sachin B Undre; Shivani R. Pandya; Vinod Kumar; Man Singh
Abstract
Developing new smart materials and tracking their structural potential have been in focus for curing disease and other applications such as catalyzing biomolecules like proteins and selective bioremediation of toxic metals, dyes, pesticides have been thrust areas of research in the field of materials ...
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Developing new smart materials and tracking their structural potential have been in focus for curing disease and other applications such as catalyzing biomolecules like proteins and selective bioremediation of toxic metals, dyes, pesticides have been thrust areas of research in the field of materials and biomaterials sciences. Since materials are most important need of the society which develops somewhere food, drug, fuel, protective cover, defense materials, fire resistant and acoustic mechanism, UV sensitive, UV absorbing, solar radiation trapping activities. In this context, the dendrimers have been considered as ideal and smart materials to be applied for wider applications and directly, indirectly or catalyze modulator and many others. Thus, the dendrimers act as smart materials and the synthesis of such architectural and potential molecules is being considered as a new thrust area for multitasking materials with better activities to catalyze chemical and biochemical processes. The multifunctional materials of multipurpose uses with several dendrimeric branching, having innumerable binding sites and are in high demands for their drug binding, loading potential and bio coatings.
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