Bindu Mangla; Vitashi Kaul; Nitika Thakur; Sudheesh K. Shukla
Abstract
Nanoparticles (NPs) are strong colloidal particles with diameters ranging from 1nm–100 nm. They comprise of macromolecular materials and can be utilized therapeutically as adjuvant in immunizations or as medication transporters. In this paper two fundamental sorts of nanoparticles are discussed ...
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Nanoparticles (NPs) are strong colloidal particles with diameters ranging from 1nm–100 nm. They comprise of macromolecular materials and can be utilized therapeutically as adjuvant in immunizations or as medication transporters. In this paper two fundamental sorts of nanoparticles are discussed i.e., metallic nanoparticle and polymeric nanoparticle. Metallic nanoparticle is nano-sized metals with measurements (length, width, thickness) inside the size range of 1nm - 100nm. The properties, advantages, disadvantages and characteristics of metal nanomaterials are discussed in brief in this review. Polymers are the most common materials for constructing nanoparticle-based drug carriers. Polymers used to form nanoparticles can be both synthetic and natural polymers. This review summarizes the synthesis and fabrication of nanomaterials. It describes about synthesis of metallic and polymeric nanomaterials as well as synthesis of quantum dots. It gives insights of fabrication of nanomaterials. Applications of nanomaterials are also included in this review mainly focusing on biosensor, gas sensor, wastewater treatment and environmental applications. The tunable surface and optical properties of nanomaterials make the perfect contender for biosensing including the analysis of ailments, cellular imaging of cancerous cell and so on. Gas sensors have been utilized in numerous applications like monitoring the oxygen content in fuel mixture, observing food decay, health monitoring etc. Nanomaterials offer the potential for the productive expulsion of pollutants and biological contaminants thus extremely valuable in environment and wastewater treatment. Nanomaterials are highly recommended in future for these properties, mainly for their use in healthcare sector.
Bindu Mangla; Sudheesh K. Shukla; Jagriti Narang; Nitika Thakur; Chaudhery Mustansar Hussain
Abstract
In current pandemic, as there is no approved specific antiviral agent for coronavirus disease (COVID-19) available till to date; Indian Ayurveda has emerged out as effective tool to control the prevailing pandemic at initial stage mainly by gearing up the immune system. Convalescent plasma therapy (CPT) ...
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In current pandemic, as there is no approved specific antiviral agent for coronavirus disease (COVID-19) available till to date; Indian Ayurveda has emerged out as effective tool to control the prevailing pandemic at initial stage mainly by gearing up the immune system. Convalescent plasma therapy (CPT) has shown a glimpse of hope and some case study supported the hypothesis that CPT could be a prospective treatment option. The current study reported first time on a real time case study in India along with the outcome that CPT could be potentially improved the treatment of severe COVID-19. The CPT results presented here have shown that clinical symptoms were significantly improved along with increase of oxyhemoglobin saturation, also increased lymphocytes count whereas decreased C-reactive proteins within 3 days without any severe adverse side effect.
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