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Development And Characterization Of Atorvastatin Calcium Loaded chitosan Nanoparticles For Sustain Drug Delivery

Afifa Bathool; Gowda D. Vishakante; Mohammed S. Khan; H.G. Shivakumar

Volume 3, Issue 6 , December 2012, , Pages 466-470

https://doi.org/10.5185/amlett.2012.icnano.153

Abstract
  The aim of this study is to formulate and characterize atorvastatin loaded chitosan loaded nanoparticles prepared by solvent evaporation method for sustained release. Low oral bioavailability of Atorvastatin calcium (14%) due to an extensive high first-pass effect makes it as prime target for oral sustained ...  Read More